BDBM12184 (2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one::CHEMBL361235::isoquinoline derivative 7

SMILES N[C@@H](C1CCCCC1)C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=JZWIQUOOJPLTGM-INIZCTEOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12184   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12184((2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroiso...)
Affinity DataIC50:  3.02E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM12184((2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroiso...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of human DPP4 expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12184((2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroiso...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM12184((2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroiso...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed