BDBM12193 2-amino-1-(2,3-dihydro-1H-isoindol-2-yl)-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butane-1,4-dione::isoquinoline derivative 16

SMILES NC(CC(=O)N1CCc2ccccc2C1)C(=O)N1Cc2ccccc2C1

InChI Key InChIKey=ALYDHKYIEHDFLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12193   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12193(2-amino-1-(2,3-dihydro-1H-isoindol-2-yl)-4-(1,2,3,...)
Affinity DataIC50:  555nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12193(2-amino-1-(2,3-dihydro-1H-isoindol-2-yl)-4-(1,2,3,...)
Affinity DataIC50:  2.09E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12193(2-amino-1-(2,3-dihydro-1H-isoindol-2-yl)-4-(1,2,3,...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed