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BDBM123034 US8742138, 19

InChI string: InChI=1S/C18H12ClNO6/c19-10-6-4-9(5-7-10)11-2-1-3-12-14(11)15(18(25)26-17(12)24)16(23)20-8-13(21)22/h1-7,24H,8H2,(H,20,23)(H,21,22)

SMILES: OC(=O)CNC(=O)c1c2c(cccc2c(O)oc1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=JYSREMXNKDHNHN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123034   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor (HIF-PH2)


(Rattus norvegicus (Rat))
BDBM123034
PNG
(US8742138, 19)
Show SMILES OC(=O)CNC(=O)c1c2c(cccc2c(O)oc1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C18H12ClNO6/c19-10-6-4-9(5-7-10)11-2-1-3-12-14(11)15(18(25)26-17(12)24)16(23)20-8-13(21)22/h1-7,24H,8H2,(H,20,23)(H,21,22)
PDB
MMDB

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PC sid
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Similars

AffyNet 
US Patent
n/an/a 150n/an/an/an/an/an/a



Betta Pharmaceuticals Co., Ltd.

US Patent


Assay Description
HIF-PHD2 activity was measured using homogeneous TR-FRET technology (see also, US2008/004817; Dao J H et al., Anal Biochem. 2009, 384:213-23). To eac...


US Patent US8742138 (2014)

More data for this
Ligand-Target Pair