BDBM1242 (Hydroxyethyl)amidosuccinoyl deriv. 14::benzyl N-[(2S,3R)-4-[(2R)-2-tert-butyl-N-(2,4-dimethylpentan-3-yl)butanediamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate

SMILES CC(C)C(NC(=O)C[C@@H](C(=O)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)(C)C)C(C)C

InChI Key InChIKey=SCXIXUQUBGZHMQ-HZFUHODCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1242   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM1242((Hydroxyethyl)amidosuccinoyl deriv. 14 | benzyl N-...)
Affinity DataIC50:  58nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Cleavage products and substrate w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed