BDBM12550 5-chloro-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]-1H-indole-2-sulfonamide::Arylsulfonamide 3b::N-[(3S)-2-oxopyrrolidin-3-yl]sulfonamide, 1s

SMILES C[C@H](N1CC[C@H](NS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)C1=O)C(=O)N1CCOCC1

InChI Key InChIKey=BHNMMFGOJRIAEZ-LRDDRELGSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12550   

TargetCoagulation factor X(Homo sapiens (Human))
Gsk

LigandPNGBDBM12550(5-chloro-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxop...)
Affinity DataKi:  90nM ΔG°:  -9.51kcal/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Gsk

LigandPNGBDBM12550(5-chloro-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxop...)
Affinity DataKi:  90nM ΔG°:  -9.61kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair