BDBM12635 (2S,5R)-1-(N-cyclopentylglycyl)-5-ethynylpyrrolidine-2-carbonitrile::(2S,5R)-1-[2-(cyclopentylamino)acetyl]-5-ethynylpyrrolidine-2-carbonitrile::C5-substituted pyrrolidine 28

SMILES O=C(CNC1CCCC1)N1[C@H](CC[C@H]1C#N)C#C

InChI Key InChIKey=PAOXGRAINLIPSS-STQMWFEESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12635   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM12635((2S,5R)-1-(N-cyclopentylglycyl)-5-ethynylpyrrolidi...)
Affinity DataKi:  22nM ΔG°:  -10.3kcal/molepH: 7.5 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM12635((2S,5R)-1-(N-cyclopentylglycyl)-5-ethynylpyrrolidi...)
Affinity DataKi: >3.00E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM12635((2S,5R)-1-(N-cyclopentylglycyl)-5-ethynylpyrrolidi...)
Affinity DataKi: >3.00E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed