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BDBM126615 US8772283, 59

InChI string: InChI=1S/C30H30N4O4/c1-3-38-33-28(35)21-11-14-23-24(15-21)37-18-34-26(20-7-5-4-6-8-20)25(32-27(23)34)19-9-12-22(13-10-19)30(31)16-29(2,36)17-30/h4-15,36H,3,16-18,31H2,1-2H3,(H,33,35)

SMILES:

InChI Key: InChIKey=WIHDTFSONPAPTN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126615   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM126615
PNG
(US8772283, 59)
Show InChI InChI=1S/C30H30N4O4/c1-3-38-33-28(35)21-11-14-23-24(15-21)37-18-34-26(20-7-5-4-6-8-20)25(32-27(23)34)19-9-12-22(13-10-19)30(31)16-29(2,36)17-30/h4-15,36H,3,16-18,31H2,1-2H3,(H,33,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 0.530n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...


US Patent US8772283 (2014)

More data for this
Ligand-Target Pair
AKT/p21CIP1


(Homo sapiens (human))
BDBM126615
PNG
(US8772283, 59)
Show InChI InChI=1S/C30H30N4O4/c1-3-38-33-28(35)21-11-14-23-24(15-21)37-18-34-26(20-7-5-4-6-8-20)25(32-27(23)34)19-9-12-22(13-10-19)30(31)16-29(2,36)17-30/h4-15,36H,3,16-18,31H2,1-2H3,(H,33,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 2.10n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...


US Patent US8772283 (2014)

More data for this
Ligand-Target Pair