BDBM126701 US8778970, 5-9

SMILES Oc1cc(CC2CCN(CCc3ccc4occc(=O)c4c3)CC2)ccc1Br

InChI Key InChIKey=DOWPQDSKPOAVOT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 126701   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126701(US8778970, 5-9)
Affinity DataKi:  0.270nM ΔG°:  -13.0kcal/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126701(US8778970, 5-9)
Affinity DataKi:  1.70nM ΔG°:  -12.0kcal/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126701(US8778970, 5-9)
Affinity DataIC50:  1.68E+4nMAssay Description:Procedure: 1. A 10 mM solution of a test drug in DMSO was serially diluted with DMSO at four 5-fold dilutions to prepare 10, 2, 0.4 and 0.08 mM DM...More data for this Ligand-Target Pair
In DepthDetails US Patent