BDBM126701 US8778970, 5-9
SMILES Oc1cc(CC2CCN(CCc3ccc4occc(=O)c4c3)CC2)ccc1Br
InChI Key InChIKey=DOWPQDSKPOAVOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 126701
Affinity DataKi: 0.270nM ΔG°: -13.0kcal/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1.70nM ΔG°: -12.0kcal/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+4nMAssay Description:Procedure: 1. A 10 mM solution of a test drug in DMSO was serially diluted with DMSO at four 5-fold dilutions to prepare 10, 2, 0.4 and 0.08 mM DM...More data for this Ligand-Target Pair