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BDBM126796 US8785489, ethyl 5-{4-methyl-2-[(pyridin-4-ylmethyl)carbamoyl]-1H-imidazol-5-yl}-1H-pyrrolo[2,3-b]pyridine-2-carboxylate

SMILES: CCOC(=O)c1cc2cc(cnc2[nH]1)-c1nc([nH]c1C)C(=O)NCc1ccncc1

InChI Key: InChIKey=BKDVYJPTBFRCIR-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126796   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metallopeptidase 13 (MMP13)


(Mus musculus (Mouse))
BDBM126796
PNG
(US8785489, ethyl 5-{4-methyl-2-[(pyridin-4-ylmethy...)
Show SMILES CCOC(=O)c1cc2cc(cnc2[nH]1)-c1nc([nH]c1C)C(=O)NCc1ccncc1
Show InChI InChI=1S/C21H20N6O3/c1-3-30-21(29)16-9-14-8-15(11-23-18(14)26-16)17-12(2)25-19(27-17)20(28)24-10-13-4-6-22-7-5-13/h4-9,11H,3,10H2,1-2H3,(H,23,26)(H,24,28)(H,25,27)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 49n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...


US Patent US8785489 (2014)


BindingDB Entry DOI: 10.7270/Q24B300F
More data for this
Ligand-Target Pair