BDBM12710 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-sulfamoylphenyl)phenyl]-1H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carboxamide::pyrazolo[4,3-d]pyrimidinone 22

SMILES COc1ccc(cc1)-n1nc(C(N)=O)c2ncn(-c3ccc(cc3)-c3ccccc3S(N)(=O)=O)c(=O)c12

InChI Key InChIKey=MCSJZAXCNUGUJU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12710   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM12710(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-sulfamoylphenyl)...)
Affinity DataKi:  1.70nM ΔG°:  -11.8kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed