BDBM12874 1-(3-amino-1,2-benzoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-3-(trifluoromethyl)-1H,4H,7H-pyrazolo[4,3-c]pyridazin-7-one::pyrazolo[4,3-c]pyridazinone 26f

SMILES CN(C)Cc1ccccc1-c1ccc(cc1)-c1nnc2c(nn(-c3ccc4onc(N)c4c3)c2c1O)C(F)(F)F

InChI Key InChIKey=IHADKCDCROVAKF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12874   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12874(1-(3-amino-1,2-benzoxazol-5-yl)-6-(4-{2-[(dimethyl...)
Affinity DataKi:  5.5nM ΔG°:  -11.1kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed