BDBM1289 3-Aminopyridin-2(1H)-one analogue 9::3-[(1-benzothiophen-2-ylmethyl)amino]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::CHEMBL121835

SMILES CCc1cc(NCc2cc3ccccc3s2)c(=O)[nH]c1C

InChI Key InChIKey=OADBKKYLMLZYPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1289   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Organon Research And Development Group

Curated by ChEMBL
LigandPNGBDBM1289(3-Aminopyridin-2(1H)-one analogue 9 | 3-[(1-benzot...)
Affinity DataIC50:  501nMAssay Description:Inhibition of HIV-1 reverse transcriptase (HIV-1 RT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1289(3-Aminopyridin-2(1H)-one analogue 9 | 3-[(1-benzot...)
Affinity DataIC50:  500nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed