BDBM1289 3-Aminopyridin-2(1H)-one analogue 9::3-[(1-benzothiophen-2-ylmethyl)amino]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::CHEMBL121835
SMILES CCc1cc(NCc2cc3ccccc3s2)c(=O)[nH]c1C
InChI Key InChIKey=OADBKKYLMLZYPI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 1289
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Organon Research And Development Group
Curated by ChEMBL
Organon Research And Development Group
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Inhibition of HIV-1 reverse transcriptase (HIV-1 RT)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 500nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair