BDBM129353 US8802686, 11

SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)CCO)ncc1C(F)(F)F

InChI Key InChIKey=OKVAXHZNBTZJCB-GHMZBOCLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 129353   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM129353(US8802686, 11)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM129353(US8802686, 11)
Affinity DataIC50:  170nMpH: 5.5 T: 2°CAssay Description:VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM129353(US8802686, 11)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...More data for this Ligand-Target Pair
In DepthDetails US Patent