BDBM12993 5-Chloro-N-({(5S)-3-[4-(dimethylamino)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide::5-chloro-N-{[(5S)-3-[4-(dimethylamino)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide::BAY 59-7939 Analog 9::US8822458, 49

SMILES CN(C)c1ccc(cc1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O

InChI Key InChIKey=SDPNOIGDWTUQEV-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12993   

TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM12993(5-Chloro-N-({(5S)-3-[4-(dimethylamino)phenyl]-2-ox...)
Affinity DataIC50:  74nMT: 25°CAssay Description:The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM12993(5-Chloro-N-({(5S)-3-[4-(dimethylamino)phenyl]-2-ox...)
Affinity DataIC50:  74nMpH: 8.3 T: 25°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed