BDBM130201 US8815881, 163

SMILES CN1C(N)=NC(C)(c2cc(Nc3ccc(cc3C(F)(F)F)C#N)ccc2F)C(C)(C)C1=O

InChI Key InChIKey=ZLVJZYYAWCAHNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130201   

TargetBeta-secretase 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM130201(US8815881, 163)
Affinity DataIC50:  62nMT: 2°CAssay Description:BACE2 enzyme ectodomain (derived from plasmid pET17b-T7-hu proBACE2) was prepared as described in Ostermann et al., Crystal Structure of Human BACE2 ...More data for this Ligand-Target Pair
In DepthDetails US Patent