BDBM130204 US8815881, 166
SMILES CN1C(N)=N[C@](C)(c2cc(Nc3cc(F)c(cc3F)C#N)ccc2F)C(C)(C)C1=O
InChI Key InChIKey=QKDQGCFCVYWBCV-OAQYLSRUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 130204
Affinity DataIC50: 80nMT: 2°CAssay Description:BACE2 enzyme ectodomain (derived from plasmid pET17b-T7-hu proBACE2) was prepared as described in Ostermann et al., Crystal Structure of Human BACE2 ...More data for this Ligand-Target Pair