BDBM130363 US8822534, Example 6-1::US8993631, 6-1

SMILES OC(=O)CCNC(=O)[C@@H](CC(O)=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=RMZNFEBJRAJZFT-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130363   

TargetMembrane metallo-endopeptidase-like 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM130363(US8822534, Example 6-1 | US8993631, 6-1)
Affinity DataIC50:  75nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane metallo-endopeptidase-like 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM130363(US8822534, Example 6-1 | US8993631, 6-1)
Affinity DataIC50:  75nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent