BDBM130381 (R)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)piperidin-4-yl]hexanoic acid (ABH-DP)

SMILES N[C@](CCCCB(O)O)(C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)C(O)=O

InChI Key InChIKey=RLPKENIQQACFGX-GOSISDBHSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130381   

TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM130381((R)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)pipe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Schistosoma mansoni (flatworms))
University Of Pennsylvania

LigandPNGBDBM130381((R)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)pipe...)
Affinity DataKd:  540nMpH: 8.5Assay Description:SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed