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BDBM130646 US8822447, 149

SMILES: CSc1nn(-c2ccccc2)c2cc(ccc12)C1=CCN(CC1)C(=O)CCN

InChI Key: InChIKey=UQPKCWARYGLLGG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ketohexokinase


(Homo sapiens (Human))
BDBM130646
PNG
(US8822447, 149)
Show SMILES CSc1nn(-c2ccccc2)c2cc(ccc12)C1=CCN(CC1)C(=O)CCN
Show InChI InChI=1S/C22H24N4OS/c1-28-22-19-8-7-17(16-10-13-25(14-11-16)21(27)9-12-23)15-20(19)26(24-22)18-5-3-2-4-6-18/h2-8,10,15H,9,11-14,23H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 480n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...


US Patent US8822447 (2014)


BindingDB Entry DOI: 10.7270/Q2M0443Q
More data for this
Ligand-Target Pair