BDBM131014 US8829000, 187

SMILES OC(=O)CCc1ncc2n1c1ccc(cc1[nH]c2=O)C(F)(F)F

InChI Key InChIKey=UFPCPUIJYWTAEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131014   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM131014(US8829000, 187)
Affinity DataIC50:  6.37E+3nMT: 2°CAssay Description:By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM131014(US8829000, 187)
Affinity DataIC50:  2nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
In DepthDetails US Patent