BDBM13139 (2S)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1b::CGS 27023A Analog 71

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@@H](C(C)C)C(=O)NO

InChI Key InChIKey=BSIZUMJRKYHEBR-KRWDZBQOSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13139   

TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM13139((2S)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  1.30E+3nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13139((2S)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DatapH: 7.5 T: 30°CAssay Description:The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed