BDBM13167 (2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)propanamido]butanoyl]-N-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide::Capped Tripeptide Analog 3::H-N-Me-Ala-Tle-Pro-(S)-tetrahydronaphth-1-yl Amide

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCc2ccccc12)C(C)(C)C

InChI Key InChIKey=JUJIMRZGUBTJRV-LRGNLBRXSA-N

Data  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13167   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  706nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-9(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataEC50:  290nMAssay Description:Inhibition of N-terminal CARD domain of caspase 9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  12nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed