BDBM13223 2-acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3-thiazole-5-carboxamide::BMS-354825 2-Amino-4-methyl-thiazole Analog 7c

SMILES CC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C

InChI Key InChIKey=PDLUGBLZZAJWKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13223   

TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
Bristol-Myers Squibb

LigandPNGBDBM13223(2-acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3...)
Affinity DataIC50:  510nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM13223(2-acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3...)
Affinity DataIC50:  480nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed