BDBM13256 BMS-354825 2-Heteroarylamino-thiazole Analog 12a::CHEMBL189776::N-(2-chloro-6-methylphenyl)-2-(pyridin-2-ylamino)-1,3-thiazole-5-carboxamide

SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2ccccn2)s1

InChI Key InChIKey=XKKXPFCQILQKNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13256   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM13256(BMS-354825 2-Heteroarylamino-thiazole Analog 12a |...)
Affinity DataIC50:  1.20nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed