BDBM133822 US8846699, 140

SMILES CN(C)CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C

InChI Key InChIKey=SHRZDXFZUPQARN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133822   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133822(US8846699, 140)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133822(US8846699, 140)
Affinity DataIC50:  751nMpH: 7.4 T: 2°CAssay Description:VEGFR2 (KDR, Proquinase) enzyme assay (auto-phosphorylation assay) was carried out by using Tyrosine Kinase Assay Kit Green (Panvera). The entire ass...More data for this Ligand-Target Pair
In DepthDetails US Patent