BDBM13394 4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy]methyl}-3-(4-methylphenyl)benzonitrile::A313326 Analogue 29

SMILES Cc1ccc(cc1)-c1cc(ccc1COC(c1cncn1C)c1ccc(cc1)C#N)C#N

InChI Key InChIKey=ZNTACQUWCXYLEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13394   

TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Globe Pharmaceutical R And Abbott Laboratories

LigandPNGBDBM13394(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50:  1.10nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM13394(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bos taurus (bovine))
Globe Pharmaceutical R And Abbott Laboratories

LigandPNGBDBM13394(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50:  2.20E+3nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed