BDBM13423 CHEMBL167368::STX 118::[3-(2-cyclohexylethyl)-4-methyl-2-oxo-2H-chromen-7-yl] sulfamate

SMILES Cc1c(CCC2CCCCC2)c(=O)oc2cc(OS(N)(=O)=O)ccc12

InChI Key InChIKey=FCGPWKCJPCLCKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13423   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13423(CHEMBL167368 | STX 118 | [3-(2-cyclohexylethyl)-4-...)
Affinity DataIC50:  59nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13423(CHEMBL167368 | STX 118 | [3-(2-cyclohexylethyl)-4-...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13423(CHEMBL167368 | STX 118 | [3-(2-cyclohexylethyl)-4-...)
Affinity DataIC50:  46nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed