BDBM13611 2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-formamidopropanoic acid)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl]benzoic acid::CHEMBL175198::Compound VI::sulfotyrosyl tripeptide analog 6

SMILES CCCCCNC(=O)[C@H](Cc1ccc(OCC(O)=O)c(c1)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCC(O)=O

InChI Key InChIKey=PUAJYWYRZTYQKS-GOTSBHOMSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13611   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM13611(2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-formamidop...)
Affinity DataKi:  220nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Rattus norvegicus (rat))
Pharmacia

LigandPNGBDBM13611(2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-formamidop...)
Affinity DataKi:  250nM ΔG°:  -8.91kcal/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair