BDBM136302 US8853224, 12::US9290501, MT-TrisMe-ImmH

SMILES CSCC(CO)(CO)NCc1c[nH]c2c1nc[nH]c2=O

InChI Key InChIKey=MZTXOEPNHJMRKL-UHFFFAOYSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 136302   

TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKi:  19nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKd:  3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKd:  4.30E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent