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BDBM136328 US8859534, 14

SMILES: FC1(F)CC(C1)NC(=O)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1

InChI Key: InChIKey=OCUWZISPCUGWIM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A (5HT1A)


(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
BDBM136328
PNG
(US8859534, 14)
Show SMILES FC1(F)CC(C1)NC(=O)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1
Show InChI InChI=1S/C24H26F2N4O2/c25-24(26)15-19(16-24)28-23(31)21-14-17-4-3-6-20(22(17)32-21)30-12-10-29(11-13-30)9-7-18-5-1-2-8-27-18/h1-6,8,14,19H,7,9-13,15-16H2,(H,28,31)
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
3.30n/an/an/an/an/an/a7.4n/a



Acturum Life Science AB

US Patent


Assay Description
Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...


US Patent US8859534 (2014)


BindingDB Entry DOI: 10.7270/Q23R0RKV
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B (5HT1B)


(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
BDBM136328
PNG
(US8859534, 14)
Show SMILES FC1(F)CC(C1)NC(=O)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1
Show InChI InChI=1S/C24H26F2N4O2/c25-24(26)15-19(16-24)28-23(31)21-14-17-4-3-6-20(22(17)32-21)30-12-10-29(11-13-30)9-7-18-5-1-2-8-27-18/h1-6,8,14,19H,7,9-13,15-16H2,(H,28,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
42n/an/an/an/an/an/a7.4n/a



Acturum Life Science AB

US Patent


Assay Description
Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...


US Patent US8859534 (2014)


BindingDB Entry DOI: 10.7270/Q23R0RKV
More data for this
Ligand-Target Pair