BDBM13740 2-(benzylamino)-5-isopropyl-5-methylthiazol-4(5H)-one::2-(benzylamino)-5-methyl-5-(propan-2-yl)-4,5-dihydro-1,3-thiazol-4-one::2-Benzylamine analog 2

SMILES CC(C)C1(C)SC(NCc2ccccc2)=NC1=O

InChI Key InChIKey=IUURRDZAZOQTCE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13740   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM13740(2-(benzylamino)-5-isopropyl-5-methylthiazol-4(5H)-...)
Affinity DataKi:  65nM ΔG°:  -9.70kcal/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed