BDBM138225 US8871738, 8

SMILES COc1ccc(cc1-c1ccc(cc1[C@@H]1CC[C@H]2[C@H](OC(=O)N12)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)[C@H]1C[C@@H](C1)C(O)=O

InChI Key InChIKey=VHUXWKLCNFBNEC-CENSFKGNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 138225   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM138225(US8871738, 8)
Affinity DataIC50:  96.5nMpH: 7.4 T: 2°CAssay Description:First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM138225(US8871738, 8)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM138225(US8871738, 8)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM138225(US8871738, 8)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed