BDBM138393 US8877786, Example 3-7::US8993631, 32-4

SMILES C[C@H](N[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C(=O)Nc1cc(O)no1)C(O)=O

InChI Key InChIKey=WTZARVQRNNDSGI-SJCJKPOMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 138393   

TargetMembrane metallo-endopeptidase-like 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM138393(US8877786, Example 3-7 | US8993631, 32-4)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeprilysin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM138393(US8877786, Example 3-7 | US8993631, 32-4)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent