BDBM139057 US8883771, 3

SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)NCc1cccc(CNC(=O)N2CC[C@H]3CC[C@H](N3C(=O)[C@H](C2)NC(=O)[C@H](C)NC)C(=O)NC(c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=ISELJTJQCKSQCK-SGPRFTBASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139057   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM139057(US8883771, 3)
Affinity DataIC50: <10nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM139057(US8883771, 3)
Affinity DataIC50: <100nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM139057(US8883771, 3)
Affinity DataIC50: <100nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In DepthDetails US Patent