BDBM13906 CHEMBL425738::ethyl 4-[(1-benzyl-1H-indazol-5-yl)amino]pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5g
SMILES CCOC(=O)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnn2c1
InChI Key InChIKey=KBVZETYUCGGMRC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 13906
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...More data for this Ligand-Target Pair