BDBM139723 US11547697, Compound 451::US9682141, 451

SMILES Clc1ncc(cc1NS(=O)(=O)c1ccccc1)-c1ccc2ncc(C(=O)N3CCOCC3)n2c1

InChI Key InChIKey=OFDUIQHTYKILRV-OGUFLRPBSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 139723   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM139723(US11547697, Compound 451 | US9682141, 451)
Affinity DataIC50: <100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent