BDBM13993 5-[3-({2-[3-hydroxy-2-(methoxycarbonyl)phenoxy]ethyl}amino)phenyl]-1,2-oxazole-3-carboxylic acid::Isoxazole carboxylic acid analog 4

SMILES COC(=O)c1c(O)cccc1OCCNc1cccc(c1)-c1cc(no1)C(O)=O

InChI Key InChIKey=GDNDGFOQLUIHEF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13993   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13993(5-[3-({2-[3-hydroxy-2-(methoxycarbonyl)phenoxy]eth...)
Affinity DataKi:  5.01E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13993(5-[3-({2-[3-hydroxy-2-(methoxycarbonyl)phenoxy]eth...)
Affinity DataKi:  6.03E+4nM ΔG°:  -5.69kcal/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed