BDBM139989 US8901140, 2::US9358227, 2

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1

InChI Key InChIKey=BXYUWIKGVQXGEA-ZUURVNMSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139989   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM139989(US8901140, 2 | US9358227, 2)
Affinity DataIC50:  6nMAssay Description:The following assay may be used to determine the activity of the compounds of the invention for inhibiting EGFR kinase activity. The half maximal inh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM139989(US8901140, 2 | US9358227, 2)
Affinity DataIC50:  6nMAssay Description:The following assay may be used to determine the activity of the compounds of the invention for inhibiting EGFR kinase activity. The half maximal inh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM139989(US8901140, 2 | US9358227, 2)
Affinity DataIC50:  3nMAssay Description:The following in vitro assay is to determine the activity of the tested compounds for inhibiting the proliferation of cancer cells, which has high ex...More data for this Ligand-Target Pair
In DepthDetails US Patent