BDBM140020 US8901310, Comparator J

SMILES Cc1ncc(NC(=O)c2ccc3c(CC[C@@H]4C[C@@](O)(CCC(F)(F)F)CC[C@@]34Cc3ccccc3)c2)c(C)n1

InChI Key InChIKey=XNVXVNJRQLVPBF-CPESWEKQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140020   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140020(US8901310, Comparator J)
Affinity DataIC50:  4.58nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140020(US8901310, Comparator J)
Affinity DataIC50:  291nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent