BDBM140174 US8901315, 382
SMILES Cc1nn(C2CCCCC2)c2sc(cc12)C(=O)Nc1ccc(nc1)C(=O)N[C@H]1CC[C@H](O)CC1
InChI Key InChIKey=PXOSBNHUMABJOZ-RUCARUNLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 140174
Affinity DataIC50: 620nMpH: 6.5 T: 2°CAssay Description:The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Daiichi Sankyo
US Patent
Daiichi Sankyo
US Patent
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair