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BDBM140242 US8906911, 51

SMILES: CO[C@@H]1COCC[C@@H]1N(C)[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(Cl)c(c1)C(F)(F)F

InChI Key: InChIKey=VVWPLOIIEPCGMY-MSRWEFABSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140242   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM140242
PNG
(US8906911, 51)
Show SMILES CO[C@@H]1COCC[C@@H]1N(C)[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C28H37ClF3N3O3/c1-33(24-7-9-38-16-25(24)37-2)19-10-17-4-3-8-27(17,13-19)26(36)35-15-20-11-21(35)14-34(20)18-5-6-23(29)22(12-18)28(30,31)32/h5-6,12,17,19-21,24-25H,3-4,7-11,13-16H2,1-2H3/t17-,19-,20+,21+,24+,25-,27-/m1/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

21n/a 43.3n/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha┬▒16 coupling protein. All compounds were dissolved in DMSO a...


US Patent US8906911 (2014)


BindingDB Entry DOI: 10.7270/Q2BV7FBV
More data for this
Ligand-Target Pair