BDBM14083 2-ketobenzothiazole 23::N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]cyclopentanecarboxamide

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6](-[#7]-[#6](=O)-[#6]-1-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-c1nc2ccccc2s1

InChI Key InChIKey=NQABUEUFRXDDFI-UHFFFAOYSA-N

Data  3 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14083   

TargetSerine protease 1(Bos taurus (bovine))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14083(2-ketobenzothiazole 23 | N-[1-(1,3-benzothiazol-2-...)
Affinity DataKi:  30nMAssay Description:Trypsin-catalyzed hydrolysis rates were measured spectrophotometrically using bovine trypsin, a chromogenic substrate in aqueous buffer, and a microp...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM14083(2-ketobenzothiazole 23 | N-[1-(1,3-benzothiazol-2-...)
Affinity DataKi:  1.23E+4nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM14083(2-ketobenzothiazole 23 | N-[1-(1,3-benzothiazol-2-...)
Affinity DataKi:  1.46E+4nM IC50:  8.20E+4nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed