BDBM140994 US10570123, Example 160::US8916576, 160

SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCCN3CCOCC3)c(OC)cc2n1

InChI Key InChIKey=KMBVJJHZAZTAPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 140994   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM140994(US10570123, Example 160 | US8916576, 160)
Affinity DataIC50:  50nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM140994(US10570123, Example 160 | US8916576, 160)
Affinity DataIC50:  50nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM140994(US10570123, Example 160 | US8916576, 160)
Affinity DataIC50: >3.00E+3nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM140994(US10570123, Example 160 | US8916576, 160)
Affinity DataIC50: >3.00E+3nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent