BDBM141000 US10570123, Example 204::US8916576, 204

SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1

InChI Key InChIKey=WIWLMHOAKGHQBF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 141000   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141000(US10570123, Example 204 | US8916576, 204)
Affinity DataIC50:  150nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141000(US10570123, Example 204 | US8916576, 204)
Affinity DataIC50:  110nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141000(US10570123, Example 204 | US8916576, 204)
Affinity DataIC50:  67nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141000(US10570123, Example 204 | US8916576, 204)
Affinity DataIC50:  151nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141000(US10570123, Example 204 | US8916576, 204)
Affinity DataIC50:  67nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141000(US10570123, Example 204 | US8916576, 204)
Affinity DataIC50:  67nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent