BDBM141016 US10570123, Example 221::US8916576, 221

SMILES CN(C)C(=O)Nc1ccccc1-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1

InChI Key InChIKey=IFIJAUOMSKQPPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141016   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141016(US10570123, Example 221 | US8916576, 221)
Affinity DataIC50:  4.90E+4nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Surface Logix

US Patent
LigandPNGBDBM141016(US10570123, Example 221 | US8916576, 221)
Affinity DataIC50:  4.90E+4nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In DepthDetails US Patent