BDBM141330 US8916577, 3

SMILES COc1cc(ccc1Nc1ncc2CCCc3c(nn(C)c3-c2n1)C(N)=O)N1CCN(C)CC1

InChI Key InChIKey=GEMLZQBJYPNJIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 141330   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141330(US8916577, 3)
Affinity DataIC50:  194nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141330(US8916577, 3)
Affinity DataIC50:  5.91E+3nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141330(US8916577, 3)
Affinity DataIC50:  1.32E+3nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In DepthDetails US Patent