BDBM141380 US8916600, 14::US9738632, Example 14

SMILES C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1cccc(c1)C(=O)N[C@@H]1CCC[C@@H]1O)c1ccc2COCOc2c1

InChI Key InChIKey=AGELDMBCFGFBAP-JECGBCDCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141380   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141380(US8916600, 14 | US9738632, Example 14)
Affinity DataIC50:  1.75nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141380(US8916600, 14 | US9738632, Example 14)
Affinity DataIC50:  1.75nMpH: 7.4 T: 2°CAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 uM. ...More data for this Ligand-Target Pair
In DepthDetails US Patent