BDBM141456 US8921368, 72
SMILES Cc1cccc(c1)-c1cc2c(N[C@@H]3CCC[C@]3(C)F)c(cnn2c1)C(N)=O
InChI Key InChIKey=RETOGHVZWDPJEU-NQIIRXRSSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 141456
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:Kinase reactions consisted of 5 ng of JAK3 enzyme, 30 uM CSKtide substrate, 0.2 uCi gamma-33P ATP,
8 uM ATP in 30 ul kinase buffer (50 mM Hepes, pH ...More data for this Ligand-Target Pair