BDBM14180 3-oxa-13,23-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-12-one::Pyrrolocarbazole Analog 22

SMILES O=C1NCc2c1c1c3ccccc3oc1c1[nH]c3ccccc3c21

InChI Key InChIKey=NHUGCPJQFQQDDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14180   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Cephalon

LigandPNGBDBM14180(3-oxa-13,23-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}...)
Affinity DataIC50:  1.11E+3nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Cephalon

LigandPNGBDBM14180(3-oxa-13,23-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed