BDBM14247 4-bromo-3-(carboxymethoxy)-5-(pyridin-3-yl)thiophene-2-carboxylic acid::Monocyclic thiophene analog 13

SMILES OC(=O)COc1c(Br)c(sc1C(O)=O)-c1cccnc1

InChI Key InChIKey=RAMPHJUWDBVCPJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14247   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14247(4-bromo-3-(carboxymethoxy)-5-(pyridin-3-yl)thiophe...)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.28kcal/molepH: 7.0 T: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed